脂多糖,来源于肠沙门氏菌肠道血清型
Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium 是来源于血清型沙门氏菌 (S. enterica) 的脂多糖内毒素和 TLR4 激活剂，是 S 型 LPS。Lipopolysaccharides, from S. enterica 具有典型的 3 部分结构：O 抗原、核心寡糖和脂质 A。Lipopolysaccharides, from S. enterica serotype typhimurium 可调控细菌在树突状细胞（DC）中的命运，决定 DC 细胞对细菌的摄取、降解和免疫功能的激活。
建议配制浓度 ≥2 mg/mL，充分涡旋震荡 10 分钟以上，必要时辅助超声。由于 LPS 具有吸附特性，分装保存时需使用硅烷化容器或低吸附离心管，使用前充分混匀。
C1q Protein (rabbit) 是一种补体蛋白，同时是经典途径的识别分子，具有多种补体相关及非补体相关功能。C1q Protein (rabbit) 可结合来自自身、非自身及改变后自身的多种配体，调控免疫细胞和非免疫细胞的功能。C1q Protein (rabbit) 可用于多种疾病的研究。
Human FASLG mRNA编码人类Fas配体（FASLG）蛋白，该蛋白属于肿瘤坏死因子超家族。FASLG的主要功能是诱导与FAS结合引发的细胞凋亡。FAS/FASLG信号通路对免疫系统调节至关重要，包括T细胞的活化诱导细胞死亡（AICD）和细胞毒性T淋巴细胞诱导的细胞死亡。该通路也与多种癌症的进展有关。
Human CCR4 mRNA编码人类CC基序趋化因子受体4 (CCR4) 蛋白，该蛋白属于G蛋白偶联受体家族。CCR4是CC趋化因子（MIP-1、RANTES、TARC和MCP-1）的受体。趋化因子是一类结构相关的小分子多肽，能够调节各种白细胞的细胞运输。趋化因子还在免疫系统的发育、稳态和功能中发挥重要作用，并对中枢神经系统细胞以及参与血管生成或血管停滞的内皮细胞产生影响。
Human TNFRSF14 mRNA 能编码人类肿瘤坏死因子受体超家族成员 14（TNFRSF14）蛋白，该蛋白属于肿瘤坏死因子受体超家族成员。TNFRSF14 在信号传导通路中发挥作用，能够激活炎症和抑制性 T 细胞免疫反应。它与单纯疱疹病毒（HSV）的病毒包膜糖蛋白 D（gD）结合，从而介导其进入细胞。
氨基酸是维持生命活动的基本组成部分，在 ATP 生成、促进核苷酸合成以及维持细胞氧化还原方面发挥作用。除此之外，氨基酸消耗失调是导致免疫细胞抗肿瘤免疫力受损的重要潜在调节机制。免疫细胞的正常运作依赖于氨基酸代谢途径来获取能量和物质，并在激活后重新编程其代谢以支持生长、增殖和效应功能。此外，特定氨基酸（如支链氨基酸、谷氨酰胺和精氨酸）的代谢紊乱会加剧线粒体功能障碍和氧化应激，从而促进心肌纤维化和心肌细胞损伤，因此开展关于氨基酸代谢相关的研究，有望发现癌症、免疫、代谢等相关疾病的潜在药物。
神经肽是神经元通过调节分泌途径产生和释放的小蛋白物质，在神经元中表达并具有递质或共递质功能，并作用于神经底物。神经肽是迄今为止大脑中最大和最多样化的信号分子，与疾病的发生和药物的开发息息相关。神经肽参与到炎症和免疫类疾病的发生，并对上皮细胞、血管细胞和结缔组织细胞的增殖和组织修复产生影响。已有研究表明，神经肽在神经系统受到挑战（如压力、损伤或滥用药物）时具有特别重要的作用。Substance P 是一种神经肽，在中枢神经系统中作为神经递质和神经调节剂，目前处于临床研究阶段，被证明与炎症过程和疼痛有关。
脂多糖,来源于肠沙门氏菌肠道血清型
Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium 是来源于血清型沙门氏菌 (S. enterica) 的脂多糖内毒素和 TLR4 激活剂，是 S 型 LPS。Lipopolysaccharides, from S. enterica 具有典型的 3 部分结构：O 抗原、核心寡糖和脂质 A。Lipopolysaccharides, from S. enterica serotype typhimurium 可调控细菌在树突状细胞（DC）中的命运，决定 DC 细胞对细菌的摄取、降解和免疫功能的激活。
建议配制浓度 ≥2 mg/mL，充分涡旋震荡 10 分钟以上，必要时辅助超声。由于 LPS 具有吸附特性，分装保存时需使用硅烷化容器或低吸附离心管，使用前充分混匀。
C1q Protein (rabbit) 是一种补体蛋白，同时是经典途径的识别分子，具有多种补体相关及非补体相关功能。C1q Protein (rabbit) 可结合来自自身、非自身及改变后自身的多种配体，调控免疫细胞和非免疫细胞的功能。C1q Protein (rabbit) 可用于多种疾病的研究。
Human FASLG mRNA编码人类Fas配体（FASLG）蛋白，该蛋白属于肿瘤坏死因子超家族。FASLG的主要功能是诱导与FAS结合引发的细胞凋亡。FAS/FASLG信号通路对免疫系统调节至关重要，包括T细胞的活化诱导细胞死亡（AICD）和细胞毒性T淋巴细胞诱导的细胞死亡。该通路也与多种癌症的进展有关。
Human CCR4 mRNA编码人类CC基序趋化因子受体4 (CCR4) 蛋白，该蛋白属于G蛋白偶联受体家族。CCR4是CC趋化因子（MIP-1、RANTES、TARC和MCP-1）的受体。趋化因子是一类结构相关的小分子多肽，能够调节各种白细胞的细胞运输。趋化因子还在免疫系统的发育、稳态和功能中发挥重要作用，并对中枢神经系统细胞以及参与血管生成或血管停滞的内皮细胞产生影响。
Human TNFRSF14 mRNA 能编码人类肿瘤坏死因子受体超家族成员 14（TNFRSF14）蛋白，该蛋白属于肿瘤坏死因子受体超家族成员。TNFRSF14 在信号传导通路中发挥作用，能够激活炎症和抑制性 T 细胞免疫反应。它与单纯疱疹病毒（HSV）的病毒包膜糖蛋白 D（gD）结合，从而介导其进入细胞。
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Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
