Human serum albumin (HSA) 是血浆中含量最高的蛋白质，是影响血浆瘤压的主要因素。Human serum albumin 具有抗氧化、抗凝血、抗炎、抗血小板聚集活性以及胶体渗透作用。Human serum albumin 能阻止 GML 抑制人类 T 细胞的能力，实现对 T 细胞功能的保护。Human serum albumin 也与心血管疾病相关，能部分阻止 LPS (HY-D1056) 诱导的氧化应激以及血管壁中 NF-κB、iNOS 和 过氧亚硝酸根 (ONOO−) 上调的血压降低。 本产品是在微生物表达系统中重组表达的人血清白蛋白。
牛乳铁蛋白
Lactoferrin from Bovine milk 是中性粒细胞释放的物质。Lactoferrin from Bovine milk 是一种具有口服活性的多功能铁结合糖蛋白。Lactoferrin from Bovine milk 可防止细胞粘附、细胞集落的生长和扩散。Lactoferrin from Bovine milk 还具有抗病毒活性，抑制微生物和病毒粘附和进入宿主细胞。此外，Lactoferrin from Bovine milk 具有抗炎、免疫调节和抗癌活性。
Phleomycin 是一种依赖铜离子的 DNA 损伤剂和抗生素，具有抗肿瘤活性。Phleomycin 通过与 DNA 结合并在还原剂 (如二硫苏糖醇、谷胱甘肽) 存在下产生 ROS，诱导 DNA 单链及双链断裂。Phleomycin 可诱导细胞凋亡或突变，被广泛应用于癌症抑制、微生物遗传转化 (作为筛选标记提高真菌转化效率) 及 DNA 修复机制研究。
大豆蛋白胨
Peptone from soya (Peptones, soybean) 是一种蛋白胨。Peptone from soya 提供氮源、碳源和其他营养成分。Peptone from soya 可以刺激/调节环状花生酸的生物合成。Peptone from soya 诱导豚鼠肺实质剂量依赖性收缩。Peptone from soya 可用于微生物和细胞培养。
Plantaricin A 是一种抗菌肽，可从植物乳杆菌 (Lactobacillus plantarum) 中提取。Plantaricin A 与环丙沙星具有协同作用。Plantaricin A 表现出抗菌活性。Plantaricin A 可以提高金黄色葡萄球菌的膜电位和细胞内活性氧 (ROS) 水平。Plantaricin A 通过与外排泵结合并改变 MepA、NorA 和 LmrS 的结构，从而抑制外排泵的功能。Plantaricin A 能显著缓解炎症，促进伤口愈合。Plantaricin A 对癌变大鼠垂体细胞具有通透化作用[1][2]。
4-Ethylphenyl sulfate sodium is an orally active and brain-penetrant gut microbial metabolite. 4-Ethylphenyl sulfate sodium downregulates Bcl2 expression, upregulates Bax expression, and induces cancer cell apoptosis via the endogenous apoptotic pathway. 4-Ethylphenyl sulfate sodium induces G2/M cell cycle arrest and reactive oxygen species (ROS) production. 4-Ethylphenyl sulfate sodium impairs oligodendrocyte maturation, reduces oligodendrocyte-neuron interactions, decreases axonal myelination levels, and shifts the oligodendrocyte population toward immature precursor cells. 4-Ethylphenyl sulfate sodium alters brain region-specific neural activity and functional connectivity in mice, and correlates with anxiety-like behaviors in mice.
Inostamycin A sodium 是一种胞苷-5’-二磷酸-1,2-二酰基-sn-甘油 (CDP-DG):肌醇转移酶抑制剂。Inostamycin A sodium 可降低磷脂酰肌醇周转，抑制细胞增殖与转化。Inostamycin A sodium 可抑制癌细胞增殖、诱导凋亡 (apoptosis)、阻止肿瘤复发。Inostamycin A sodium 具有抗菌。Inostamycin A sodium 可用于感染、癌症的相关研究。
Alamethicin F 50 是一种抗生素。Alamethicin F 50 由膜活性肽组成，含有 75% Alamethicin F 50/5 和 10% Alamethicin F 50/7。Alamethicin F 50 通过破坏微生物细胞膜的完整性，导致细胞内容物泄漏和微生物死亡，从而表现出抗真菌和抗菌活性。Alamethicin F 50 能够降低水的表面张力，可用作表面活性剂或洗涤剂。
尿石素C (标准品)
Urolithin C (Standard) 是 Urolithin C 的分析标准品。本产品用于研究及分析应用。Urolithin C， 是鞣花酸的多酚类肠道微生物代谢产物，是胰岛素分泌 (insulin secretion) 的葡萄糖依赖性激活剂。Urolithin C 是一种 L 型 Ca2+ 通道开放剂，可增强 Ca2+ 的流入。Urolithin C 通过线粒体介导的途径诱导细胞凋亡 (apoptosis
Tachyplesin II 是一种广谱的阳离子抗菌肽。Tachyplesin II 对革兰氏阳性菌、革兰氏阴性菌和部分真菌均有显著的抑制效果。Tachyplesin II 通过正电荷与细菌膜脂多糖结合，破坏膜完整性，导致细胞内容物泄漏。Tachyplesin II 可结合 DNA 小沟，抑制微生物复制，还能抑制 HIV-1 复制和肝癌细胞增殖。
鱼明胶,suitable for cell culture
Fish Gelatin,suitable for cell culture 是一种天然生物聚合物。Fish Gelatin,suitable for cell culture 可从鱼类加工副产物中分离得到，例如鱼皮、鱼鳞、鱼骨和鱼鳔。Fish Gelatin,suitable for cell culture 已被认为是哺乳动物明胶的可行替代品。经修饰的 Fish Gelatin 在纳米材料、3D 打印、薄膜、涂层和生物制剂等多个行业中显示出巨大应用前景。Fish Gelatin,suitable for cell culture 适用于细胞培养，可用于细胞培养实验。
代谢组学是对生物系统中的小分子代谢物进行系统表征的学科，已成为植物科学、微生物生物技术和生物医学研究领域基础研究和转化应用中不可或缺的分析平台。作为多组学整合的重要组成部分，该学科可解读在基因组、转录组和蛋白质组调控下游运行的错综复杂的分子网络，从而捕捉最接近生物体功能的动态生化表型。代谢组由分子量通常低于 1500 Da 的内源化合物组成，是细胞过程和环境相互作用的功能读数，代谢网络的扰动往往与疾病的发病机制有关。这些独特的属性促使代谢组学在药理学研究中发挥着举足轻重的作用，尤其是在靶点解构、药效学评估和病理过程的机理阐明方面。
Human serum albumin (HSA) 是血浆中含量最高的蛋白质，是影响血浆瘤压的主要因素。Human serum albumin 具有抗氧化、抗凝血、抗炎、抗血小板聚集活性以及胶体渗透作用。Human serum albumin 能阻止 GML 抑制人类 T 细胞的能力，实现对 T 细胞功能的保护。Human serum albumin 也与心血管疾病相关，能部分阻止 LPS (HY-D1056) 诱导的氧化应激以及血管壁中 NF-κB、iNOS 和 过氧亚硝酸根 (ONOO−) 上调的血压降低。 本产品是在微生物表达系统中重组表达的人血清白蛋白。
牛乳铁蛋白
Lactoferrin from Bovine milk 是中性粒细胞释放的物质。Lactoferrin from Bovine milk 是一种具有口服活性的多功能铁结合糖蛋白。Lactoferrin from Bovine milk 可防止细胞粘附、细胞集落的生长和扩散。Lactoferrin from Bovine milk 还具有抗病毒活性，抑制微生物和病毒粘附和进入宿主细胞。此外，Lactoferrin from Bovine milk 具有抗炎、免疫调节和抗癌活性。
大豆蛋白胨
Peptone from soya (Peptones, soybean) 是一种蛋白胨。Peptone from soya 提供氮源、碳源和其他营养成分。Peptone from soya 可以刺激/调节环状花生酸的生物合成。Peptone from soya 诱导豚鼠肺实质剂量依赖性收缩。Peptone from soya 可用于微生物和细胞培养。
鱼明胶,suitable for cell culture
Fish Gelatin,suitable for cell culture 是一种天然生物聚合物。Fish Gelatin,suitable for cell culture 可从鱼类加工副产物中分离得到，例如鱼皮、鱼鳞、鱼骨和鱼鳔。Fish Gelatin,suitable for cell culture 已被认为是哺乳动物明胶的可行替代品。经修饰的 Fish Gelatin 在纳米材料、3D 打印、薄膜、涂层和生物制剂等多个行业中显示出巨大应用前景。Fish Gelatin,suitable for cell culture 适用于细胞培养，可用于细胞培养实验。
Plantaricin A 是一种抗菌肽，可从植物乳杆菌 (Lactobacillus plantarum) 中提取。Plantaricin A 与环丙沙星具有协同作用。Plantaricin A 表现出抗菌活性。Plantaricin A 可以提高金黄色葡萄球菌的膜电位和细胞内活性氧 (ROS) 水平。Plantaricin A 通过与外排泵结合并改变 MepA、NorA 和 LmrS 的结构，从而抑制外排泵的功能。Plantaricin A 能显著缓解炎症，促进伤口愈合。Plantaricin A 对癌变大鼠垂体细胞具有通透化作用[1][2]。
Alamethicin F 50 是一种抗生素。Alamethicin F 50 由膜活性肽组成，含有 75% Alamethicin F 50/5 和 10% Alamethicin F 50/7。Alamethicin F 50 通过破坏微生物细胞膜的完整性，导致细胞内容物泄漏和微生物死亡，从而表现出抗真菌和抗菌活性。Alamethicin F 50 能够降低水的表面张力，可用作表面活性剂或洗涤剂。
Tachyplesin II 是一种广谱的阳离子抗菌肽。Tachyplesin II 对革兰氏阳性菌、革兰氏阴性菌和部分真菌均有显著的抑制效果。Tachyplesin II 通过正电荷与细菌膜脂多糖结合，破坏膜完整性，导致细胞内容物泄漏。Tachyplesin II 可结合 DNA 小沟，抑制微生物复制，还能抑制 HIV-1 复制和肝癌细胞增殖。
Phleomycin 是一种依赖铜离子的 DNA 损伤剂和抗生素，具有抗肿瘤活性。Phleomycin 通过与 DNA 结合并在还原剂 (如二硫苏糖醇、谷胱甘肽) 存在下产生 ROS，诱导 DNA 单链及双链断裂。Phleomycin 可诱导细胞凋亡或突变，被广泛应用于癌症抑制、微生物遗传转化 (作为筛选标记提高真菌转化效率) 及 DNA 修复机制研究。
4-Ethylphenyl sulfate sodium is an orally active and brain-penetrant gut microbial metabolite. 4-Ethylphenyl sulfate sodium downregulates Bcl2 expression, upregulates Bax expression, and induces cancer cell apoptosis via the endogenous apoptotic pathway. 4-Ethylphenyl sulfate sodium induces G2/M cell cycle arrest and reactive oxygen species (ROS) production. 4-Ethylphenyl sulfate sodium impairs oligodendrocyte maturation, reduces oligodendrocyte-neuron interactions, decreases axonal myelination levels, and shifts the oligodendrocyte population toward immature precursor cells. 4-Ethylphenyl sulfate sodium alters brain region-specific neural activity and functional connectivity in mice, and correlates with anxiety-like behaviors in mice.
尿石素C (标准品)
Urolithin C (Standard) 是 Urolithin C 的分析标准品。本产品用于研究及分析应用。Urolithin C， 是鞣花酸的多酚类肠道微生物代谢产物，是胰岛素分泌 (insulin secretion) 的葡萄糖依赖性激活剂。Urolithin C 是一种 L 型 Ca2+ 通道开放剂，可增强 Ca2+ 的流入。Urolithin C 通过线粒体介导的途径诱导细胞凋亡 (apoptosis
Urolithin A-13C6 是 13C-标记的 Urolithin A (HY-100599)。Urolithin A，鞣花酸的肠道微生物代谢产物，具有抗炎、抗增殖和抗氧化的特性。Urolithin A 诱导自噬 (autophagy) 和凋亡 (apoptosis)，抑制细胞周期进程，抑制 DNA 合成。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
![[BMIM]Cl](http://hg.y866.cn/biomolecule/lib/file/product_pic/hy-w016758.gif)
