莱苞迪苷D
Rebaudioside D 是一种口服有效的甜味剂，靶向激活 FXR、调节 Acetyl-CoA Carboxylase 和抑制 3-hydroxy-3-methylglutaryl-CoA reductase。Rebaudioside D 调控胆汁酸稳态与脂质代谢，降低脂肪酸与胆固醇的合成速率，具有抗脂肪生成、保肝、抗脂肪变性、调节肠道菌群、增强次级胆汁酸代谢、抗内毒素、调控胆汁酸转运及抑制胆汁酸外排等多重作用。Rebaudioside D 还减少体重增长、内脏脂肪堆积、肝脏甘油三酯与胆固醇蓄积、肝脏脂质过氧化，并降低循环中脂多糖结合蛋白的水平。Rebaudioside D 还增强肠道细菌次级胆汁酸代谢通路，上调回肠有机溶质转运蛋白 α 的基因表达，下调肝脏胆盐输出泵蛋白的基因表达。Rebaudioside D 不影响葡萄糖稳态、改变总热量摄入或粪便能量排泄、诱导体重增加、加重肥胖、促进肝脏脂肪变性、损伤棕色脂肪组织功能，也不会改变骨骼肌代谢相关蛋白。Rebaudioside D 可用于饮食诱导肥胖及肥胖相关研究。
Plantaricin A 是一种抗菌肽，可从植物乳杆菌 (Lactobacillus plantarum) 中提取。Plantaricin A 与环丙沙星具有协同作用。Plantaricin A 表现出抗菌活性。Plantaricin A 可以提高金黄色葡萄球菌的膜电位和细胞内活性氧 (ROS) 水平。Plantaricin A 通过与外排泵结合并改变 MepA、NorA 和 LmrS 的结构，从而抑制外排泵的功能。Plantaricin A 能显著缓解炎症，促进伤口愈合。Plantaricin A 对癌变大鼠垂体细胞具有通透化作用[1][2]。
Boeravinone B (Standard)是 Boeravinone B 的分析标准品。本产品用于研究及分析应用。Boeravinone B 是金黄色葡萄球菌和人 P-糖蛋白 NorA 菌外排泵的双抑制剂，可减少细菌生物膜的形成和入侵。Boeravinone B在氧化应激中具有抗衰老和抗凋亡的作用。
Antibacterial Library contains about 32,000 compounds, and is designed for discovery of novel antibacterials. The new antibacterial library uses substructure and shape-based searches to select molecules with privileged cores, motifs, and natural product-like scaffolds that are known to be critical for antibacterial activity.
Plantaricin A 是一种抗菌肽，可从植物乳杆菌 (Lactobacillus plantarum) 中提取。Plantaricin A 与环丙沙星具有协同作用。Plantaricin A 表现出抗菌活性。Plantaricin A 可以提高金黄色葡萄球菌的膜电位和细胞内活性氧 (ROS) 水平。Plantaricin A 通过与外排泵结合并改变 MepA、NorA 和 LmrS 的结构，从而抑制外排泵的功能。Plantaricin A 能显著缓解炎症，促进伤口愈合。Plantaricin A 对癌变大鼠垂体细胞具有通透化作用[1][2]。
莱苞迪苷D
Rebaudioside D 是一种口服有效的甜味剂，靶向激活 FXR、调节 Acetyl-CoA Carboxylase 和抑制 3-hydroxy-3-methylglutaryl-CoA reductase。Rebaudioside D 调控胆汁酸稳态与脂质代谢，降低脂肪酸与胆固醇的合成速率，具有抗脂肪生成、保肝、抗脂肪变性、调节肠道菌群、增强次级胆汁酸代谢、抗内毒素、调控胆汁酸转运及抑制胆汁酸外排等多重作用。Rebaudioside D 还减少体重增长、内脏脂肪堆积、肝脏甘油三酯与胆固醇蓄积、肝脏脂质过氧化，并降低循环中脂多糖结合蛋白的水平。Rebaudioside D 还增强肠道细菌次级胆汁酸代谢通路，上调回肠有机溶质转运蛋白 α 的基因表达，下调肝脏胆盐输出泵蛋白的基因表达。Rebaudioside D 不影响葡萄糖稳态、改变总热量摄入或粪便能量排泄、诱导体重增加、加重肥胖、促进肝脏脂肪变性、损伤棕色脂肪组织功能，也不会改变骨骼肌代谢相关蛋白。Rebaudioside D 可用于饮食诱导肥胖及肥胖相关研究。
Boeravinone B (Standard)是 Boeravinone B 的分析标准品。本产品用于研究及分析应用。Boeravinone B 是金黄色葡萄球菌和人 P-糖蛋白 NorA 菌外排泵的双抑制剂，可减少细菌生物膜的形成和入侵。Boeravinone B在氧化应激中具有抗衰老和抗凋亡的作用。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
