Tetrindole hydrochloride 是单胺氧化酶 A (MAO A) 的选择性抑制剂。Tetrindole hydrochloride 以竞争性方式抑制大鼠脑线粒体 MAO A，Ki 值为 0.4 μM，抑制 MAO B 的 Ki 为 110 μM。Tetrindole hydrochloride 具有抗抑郁活性。
1-Methyl-2-undecyl-4(1H)-quinolone 是一种有效的不可逆和选择性 B 型单胺氧化酶 (MAO-B) 抑制剂。1-Methyl-2-undecyl-4(1H)-quinolone 对 MAO-B 有选择性抑制作用，IC50 和 Ki 值分别为 15.3 μM和 9.91 μM，但对 A 型 MAO (MAO-A) 活性没有抑制作用。1-Methyl-2-undecyl-4(1H)-quinolone 是一种喹诺酮类生物碱，从Evodia rutaecarpa HOOK. f. et THOMS 鲜叶和果实中分离得到。
亚甲蓝三水合物
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) 是一种鸟苷酸环化酶 (sGC)，单胺氧化酶 A (MAO-A) 和 NO 合酶 (NOS) 抑制剂。Methylene blue trihydrate 是一种血管加压药，在医疗中通常用作染料。Methylene blue trihydrate 具有抗伤害感受，抗疟疾，抗抑郁和抗焦虑作用，可用于高铁血红蛋白血症，神经退行性疾病和异环磷酰胺引起的脑病的研究。
假马齿苋皂苷I
Bacopaside I 是一种口服有效的水通道蛋白 AQP1 抑制剂与 PKC 调节剂，具有神经保护活性和抗癌活性。Bacopaside I 能特异性阻断 AQP1 的水通道及 cGMP 门控离子通道活性而不影响 AQP4，从而抑制表达 AQP1 的结肠癌细胞迁移。Bacopaside I 通过与 PI3K 相互作用激活 Akt 通路，特异性抑制 MAO-A，有效减轻氧糖剥夺诱导的神经元坏死与凋亡 (apoptosis)，降低氧化应激并调节神经受体表面表达。Bacopaside I 与 Bacopaside II (HY-N6016) 联用时，Bacopaside I 能显著降低乳腺癌细胞的活力、增殖及侵袭能力，并能够结合孕烷 X 受体 (PXR)。Bacopaside I 可用于结肠癌、乳腺癌、血管性痴呆及脑缺血等相关疾病的研究。
假马齿苋皂苷I (标准品)
Bacopaside I (Standard) 是 Bacopaside I 的分析标准品。本产品用于研究及分析应用。Bacopaside I 是一种口服有效的水通道蛋白 AQP1 抑制剂与 PKC 调节剂，具有神经保护活性和抗癌活性。Bacopaside I 能特异性阻断 AQP1 的水通道及 cGMP 门控离子通道活性而不影响 AQP4，从而抑制表达 AQP1 的结肠癌细胞迁移。Bacopaside I 通过与 PI3K 相互作用激活 Akt 通路，特异性抑制 MAO-A，有效减轻氧糖剥夺诱导的神经元坏死与凋亡 (apoptosis)，降低氧化应激并调节神经受体表面表达。Bacopaside I 与 Bacopaside II (HY-N6016) 联用时，Bacopaside I 能显著降低乳腺癌细胞的活力、增殖及侵袭能力，并能够结合孕烷 X 受体 (PXR)。Bacopaside I 可用于结肠癌、乳腺癌、血管性痴呆及脑缺血等相关疾病的研究。
假马齿苋皂苷I
Bacopaside I 是一种口服有效的水通道蛋白 AQP1 抑制剂与 PKC 调节剂，具有神经保护活性和抗癌活性。Bacopaside I 能特异性阻断 AQP1 的水通道及 cGMP 门控离子通道活性而不影响 AQP4，从而抑制表达 AQP1 的结肠癌细胞迁移。Bacopaside I 通过与 PI3K 相互作用激活 Akt 通路，特异性抑制 MAO-A，有效减轻氧糖剥夺诱导的神经元坏死与凋亡 (apoptosis)，降低氧化应激并调节神经受体表面表达。Bacopaside I 与 Bacopaside II (HY-N6016) 联用时，Bacopaside I 能显著降低乳腺癌细胞的活力、增殖及侵袭能力，并能够结合孕烷 X 受体 (PXR)。Bacopaside I 可用于结肠癌、乳腺癌、血管性痴呆及脑缺血等相关疾病的研究。
1-Methyl-2-undecyl-4(1H)-quinolone 是一种有效的不可逆和选择性 B 型单胺氧化酶 (MAO-B) 抑制剂。1-Methyl-2-undecyl-4(1H)-quinolone 对 MAO-B 有选择性抑制作用，IC50 和 Ki 值分别为 15.3 μM和 9.91 μM，但对 A 型 MAO (MAO-A) 活性没有抑制作用。1-Methyl-2-undecyl-4(1H)-quinolone 是一种喹诺酮类生物碱，从Evodia rutaecarpa HOOK. f. et THOMS 鲜叶和果实中分离得到。
假马齿苋皂苷I (标准品)
Bacopaside I (Standard) 是 Bacopaside I 的分析标准品。本产品用于研究及分析应用。Bacopaside I 是一种口服有效的水通道蛋白 AQP1 抑制剂与 PKC 调节剂，具有神经保护活性和抗癌活性。Bacopaside I 能特异性阻断 AQP1 的水通道及 cGMP 门控离子通道活性而不影响 AQP4，从而抑制表达 AQP1 的结肠癌细胞迁移。Bacopaside I 通过与 PI3K 相互作用激活 Akt 通路，特异性抑制 MAO-A，有效减轻氧糖剥夺诱导的神经元坏死与凋亡 (apoptosis)，降低氧化应激并调节神经受体表面表达。Bacopaside I 与 Bacopaside II (HY-N6016) 联用时，Bacopaside I 能显著降低乳腺癌细胞的活力、增殖及侵袭能力，并能够结合孕烷 X 受体 (PXR)。Bacopaside I 可用于结肠癌、乳腺癌、血管性痴呆及脑缺血等相关疾病的研究。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
