脂多糖,来源于肠沙门氏菌肠道血清型
Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium 是来源于血清型沙门氏菌 (S. enterica) 的脂多糖内毒素和 TLR4 激活剂,是 S 型 LPS。Lipopolysaccharides, from S. enterica 具有典型的 3 部分结构:O 抗原、核心寡糖和脂质 A。Lipopolysaccharides, from S. enterica serotype typhimurium 可调控细菌在树突状细胞(DC)中的命运,决定 DC 细胞对细菌的摄取、降解和免疫功能的激活。
建议配制浓度 ≥2 mg/mL,充分涡旋震荡 10 分钟以上,必要时辅助超声。由于 LPS 具有吸附特性,分装保存时需使用硅烷化容器或低吸附离心管,使用前充分混匀。
甲嘧磺隆 (标准品)
Sulfometuron-methyl (Standard)是 Sulfometuron-methyl 的分析标准品。本产品用于研究及分析应用。Sulfometuron-methyl 是除草剂,也是一种强效的酶乙酰乳酸合成酶 (ALS) 抑制剂。Sulfometuron-methyl 具有抗细菌和抗真菌活性,能抑制鼠伤寒沙门氏菌 ALS II 和大肠杆菌 ALS III 的活性。
Amicoumacin A 是一种具有口服活性的抗生素 (Antibiotic)。Amicoumacin A 以细菌核糖体为作用靶点,通过稳定 mRNA 与核糖体的相互作用抑制细菌翻译。Amicoumacin A 通过靶向真核核糖体诱导癌细胞死亡。Amicoumacin A 具有抗炎和抗溃疡活性,抑制角叉菜胶诱导的爪水肿,预防应激诱导的胃溃疡。Amicoumacin A 抑制革兰氏阳性菌、沙门氏菌属、志贺氏菌属、幽门螺杆菌以及耐甲氧西林金黄色葡萄球菌的生长。Amicoumacin A 可用于肺癌、乳腺癌、细菌感染、炎症水肿及胃溃疡的研究。
萘啶酸
Nalidixic acid,一种喹诺酮类抗生素 (antibiotic),对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid 在较低浓度下以抑菌的方式起作用,而在较高浓度下具有杀菌作用。Nalidixic acid 抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基,并可逆地阻止易感细菌中的 DNA 复制。
萘啶酮酸
Nalidixic acid sodium salt,一种喹诺酮类抗生素 (antibiotic),对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid sodium salt 在较低浓度下以抑菌的方式起作用,而在较高浓度下具有杀菌作用。Nalidixic acid sodium salt 抑制 DNA 促旋酶和拓扑异构酶IV的亚基,并可逆地阻止易感细菌中的 DNA 复制。
Flagellin from S. typhimurium 是一种有效的 TLR5 激动剂。Flagellin from S. typhimurium 可以激活免疫细胞,抑制黑色素瘤细胞的活性。Flagellin from S. typhimurium 激活细胞中依赖于 TLR5/MyD88/TRAF6 信号轴的 NF-κB 通路。Flagellin from S. typhimurium 可通过促进 IL-8 生成、抑制 IL-10 生成并提高 IFN-γ/IL-10 比值,在原代鸡肝细胞-非实质细胞共培养体系中诱导促炎反应。Flagellin from S. typhimurium 可用于黑色素瘤、炎症疾病的研究。
Flagellin from S. typhimurium 是一种有效的 TLR5 激动剂。Flagellin from S. typhimurium 可以激活免疫细胞,抑制黑色素瘤细胞的活性。Flagellin from S. typhimurium 激活细胞中依赖于 TLR5/MyD88/TRAF6 信号轴的 NF-κB 通路。Flagellin from S. typhimurium 可通过促进 IL-8 生成、抑制 IL-10 生成并提高 IFN-γ/IL-10 比值,在原代鸡肝细胞-非实质细胞共培养体系中诱导促炎反应。Flagellin from S. typhimurium 可用于黑色素瘤、炎症疾病的研究。
脂多糖,来源于肠沙门氏菌肠道血清型
Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium 是来源于血清型沙门氏菌 (S. enterica) 的脂多糖内毒素和 TLR4 激活剂,是 S 型 LPS。Lipopolysaccharides, from S. enterica 具有典型的 3 部分结构:O 抗原、核心寡糖和脂质 A。Lipopolysaccharides, from S. enterica serotype typhimurium 可调控细菌在树突状细胞(DC)中的命运,决定 DC 细胞对细菌的摄取、降解和免疫功能的激活。
建议配制浓度 ≥2 mg/mL,充分涡旋震荡 10 分钟以上,必要时辅助超声。由于 LPS 具有吸附特性,分装保存时需使用硅烷化容器或低吸附离心管,使用前充分混匀。
萘啶酸
Nalidixic acid,一种喹诺酮类抗生素 (antibiotic),对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid 在较低浓度下以抑菌的方式起作用,而在较高浓度下具有杀菌作用。Nalidixic acid 抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基,并可逆地阻止易感细菌中的 DNA 复制。
Amicoumacin A 是一种具有口服活性的抗生素 (Antibiotic)。Amicoumacin A 以细菌核糖体为作用靶点,通过稳定 mRNA 与核糖体的相互作用抑制细菌翻译。Amicoumacin A 通过靶向真核核糖体诱导癌细胞死亡。Amicoumacin A 具有抗炎和抗溃疡活性,抑制角叉菜胶诱导的爪水肿,预防应激诱导的胃溃疡。Amicoumacin A 抑制革兰氏阳性菌、沙门氏菌属、志贺氏菌属、幽门螺杆菌以及耐甲氧西林金黄色葡萄球菌的生长。Amicoumacin A 可用于肺癌、乳腺癌、细菌感染、炎症水肿及胃溃疡的研究。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.