刺五加皂苷 B
Ciwujianoside B 是一种具有口服活性且可穿透血脑屏障的辐射防护剂和记忆增强剂。Ciwujianoside B 减少辐射诱导的 DNA 损伤、细胞周期阻滞和凋亡 (apoptosis)、下调 NF-κB 和 Bax/Bcl-2 比值，增强骨髓细胞增殖能力。Ciwujianoside B 可增强正常小鼠的物体识别记忆，并诱导原代培养皮质神经元的树突延伸。Ciwujianoside B 可用于造血系统辐射损伤和记忆增强相关研究。
五味子酯乙
Schisantherin B (Gomisin-B) 是一种木脂素类化合物，是五味子的活性成分之一。Schisantherin B 可激活 PI3K/AKT 信号通路，恢复 GSK3β 的活性，并减少海马体和大脑皮层组织中的 tau 蛋白过度磷酸化。Schisantherin B 可上调 GLT-1 水平，降低促炎细胞因子 TNF-α/IL-1β/IL-6 的表达，上调 IL-10 的表达，并抑制细胞凋亡 (apoptosis)。Schisantherin B 可用于脊髓损伤、阿尔茨海默病和抑郁症研究。
Cistanoside H 是一种苯乙醇苷类神经保护剂，能够从 Callicarpa dichotoma (二色紫珠) 的叶和嫩枝中分离得到。Cistanoside H 能够减轻谷氨酸诱导的氧化应激、保护大鼠皮质细胞免受神经毒性损伤。Cistanoside H 保护神经细胞、抵御兴奋性毒性损伤，可应用于神经退行性疾病 (如阿尔茨海默病、帕金森病) 相关研究。
五味子酯乙 (标准品)
Schisantherin B (Gomisin-B) (Standard) 是 Schisantherin B 的分析标准品。本产品用于研究及分析应用。Schisantherin B (Gomisin-B) 是一种木脂素类化合物，是五味子的活性成分之一。Schisantherin B 可激活 PI3K/AKT 信号通路，恢复 GSK3β 的活性，并减少海马体和大脑皮层组织中的 tau 蛋白过度磷酸化。Schisantherin B 可上调 GLT-1 水平，降低促炎细胞因子 TNF−α/IL−1β/IL−6 的表达，上调 IL−10 的表达，并抑制细胞凋亡 (apoptosis)。Schisantherin B 可用于脊髓损伤、阿尔茨海默病和抑郁症研究。
寡霉素 B
Oligomycin B 是一种抗生素 (antibiotic)，可作为 ATP 合酶 (ATP Synthase) 的非选择性抑制剂。Oligomycin B 可升高线粒体膜电位。Oligomycin B 诱导细胞凋亡 (apoptosis) 和坏死。Oligomycin B 会削弱葡萄霜霉菌游动孢子的运动能力并诱导其裂解。Oligomycin B 抑制小麦稻瘟病菌，并抑制小麦瘟病的发生。Oligomycin B 可降低灰葡萄孢菌的菌丝生长与孢子萌发水平，保护拟南芥抵御灰葡萄孢菌的侵害。Oligomycin B 会加重大脑皮质挫伤大鼠的脑细胞毒性水肿，升高颅内压与脑含水量，并加剧其线粒体损伤。Oligomycin B 可用于葡萄霜霉病、创伤性脑损伤、小麦瘟病、灰霉病的相关研究。
赭曲霉毒素 A
Ochratoxin A 是一种可穿透血脑屏障的食源性真菌毒素，是曲霉属 (Aspergillus) 和青霉属 (Penicillium) 真菌的次生代谢产物，属于 2B 类致癌物。Ochratoxin A 诱导氧化应激、抑制线粒体呼吸、造成氧化性 DNA 损伤、破坏 PPAR-γ-CD36 轴、诱导免疫抑制、介导线粒体依赖性凋亡 (apoptosis)、抑制谷氨酸吸收、引发脱髓鞘病变与神经炎症、导致 DNA 低甲基化及抑制细胞增殖等途径。Ochratoxin A 可诱发肾毒性、肝毒性、免疫毒性、神经毒性，还具有致突变性、致畸性与致癌性。
Tovophyllin A 是一种具有口服活性的呫吨酮类化合物。Tovophyllin A 可激活 Akt/GSK3β 信号通路实现对帕金森病的神经保护作用。Tovophyllin A 可通过激活 Nrf2 对肝损伤小鼠模型发挥保护作用。Tovophyllin A 对急性肺损伤小鼠有保护性抗炎活性。Tovophyllin A 可抑制 NF-κB 的活化及后续促炎细胞因子的释放。Tovophyllin A 可减少凋亡细胞凋亡 (Apoptosis)。Tovophyllin A 具有抗疟原虫活性。Tovophyllin A 对肺上皮癌细胞和乳腺癌细胞具有细胞毒性活性。Tovophyllin A 可用于帕金森病、肝损伤、急性肺损伤、肺上皮癌以及乳腺癌的相关研究。
寡霉素 B
Oligomycin B 是一种抗生素 (antibiotic)，可作为 ATP 合酶 (ATP Synthase) 的非选择性抑制剂。Oligomycin B 可升高线粒体膜电位。Oligomycin B 诱导细胞凋亡 (apoptosis) 和坏死。Oligomycin B 会削弱葡萄霜霉菌游动孢子的运动能力并诱导其裂解。Oligomycin B 抑制小麦稻瘟病菌，并抑制小麦瘟病的发生。Oligomycin B 可降低灰葡萄孢菌的菌丝生长与孢子萌发水平，保护拟南芥抵御灰葡萄孢菌的侵害。Oligomycin B 会加重大脑皮质挫伤大鼠的脑细胞毒性水肿，升高颅内压与脑含水量，并加剧其线粒体损伤。Oligomycin B 可用于葡萄霜霉病、创伤性脑损伤、小麦瘟病、灰霉病的相关研究。
赭曲霉毒素 A
Ochratoxin A 是一种可穿透血脑屏障的食源性真菌毒素，是曲霉属 (Aspergillus) 和青霉属 (Penicillium) 真菌的次生代谢产物，属于 2B 类致癌物。Ochratoxin A 诱导氧化应激、抑制线粒体呼吸、造成氧化性 DNA 损伤、破坏 PPAR-γ-CD36 轴、诱导免疫抑制、介导线粒体依赖性凋亡 (apoptosis)、抑制谷氨酸吸收、引发脱髓鞘病变与神经炎症、导致 DNA 低甲基化及抑制细胞增殖等途径。Ochratoxin A 可诱发肾毒性、肝毒性、免疫毒性、神经毒性，还具有致突变性、致畸性与致癌性。
刺五加皂苷 B
Ciwujianoside B 是一种具有口服活性且可穿透血脑屏障的辐射防护剂和记忆增强剂。Ciwujianoside B 减少辐射诱导的 DNA 损伤、细胞周期阻滞和凋亡 (apoptosis)、下调 NF-κB 和 Bax/Bcl-2 比值，增强骨髓细胞增殖能力。Ciwujianoside B 可增强正常小鼠的物体识别记忆，并诱导原代培养皮质神经元的树突延伸。Ciwujianoside B 可用于造血系统辐射损伤和记忆增强相关研究。
五味子酯乙
Schisantherin B (Gomisin-B) 是一种木脂素类化合物，是五味子的活性成分之一。Schisantherin B 可激活 PI3K/AKT 信号通路，恢复 GSK3β 的活性，并减少海马体和大脑皮层组织中的 tau 蛋白过度磷酸化。Schisantherin B 可上调 GLT-1 水平，降低促炎细胞因子 TNF-α/IL-1β/IL-6 的表达，上调 IL-10 的表达，并抑制细胞凋亡 (apoptosis)。Schisantherin B 可用于脊髓损伤、阿尔茨海默病和抑郁症研究。
五味子酯乙 (标准品)
Schisantherin B (Gomisin-B) (Standard) 是 Schisantherin B 的分析标准品。本产品用于研究及分析应用。Schisantherin B (Gomisin-B) 是一种木脂素类化合物，是五味子的活性成分之一。Schisantherin B 可激活 PI3K/AKT 信号通路，恢复 GSK3β 的活性，并减少海马体和大脑皮层组织中的 tau 蛋白过度磷酸化。Schisantherin B 可上调 GLT-1 水平，降低促炎细胞因子 TNF−α/IL−1β/IL−6 的表达，上调 IL−10 的表达，并抑制细胞凋亡 (apoptosis)。Schisantherin B 可用于脊髓损伤、阿尔茨海默病和抑郁症研究。
Cistanoside H 是一种苯乙醇苷类神经保护剂，能够从 Callicarpa dichotoma (二色紫珠) 的叶和嫩枝中分离得到。Cistanoside H 能够减轻谷氨酸诱导的氧化应激、保护大鼠皮质细胞免受神经毒性损伤。Cistanoside H 保护神经细胞、抵御兴奋性毒性损伤，可应用于神经退行性疾病 (如阿尔茨海默病、帕金森病) 相关研究。
Tovophyllin A 是一种具有口服活性的呫吨酮类化合物。Tovophyllin A 可激活 Akt/GSK3β 信号通路实现对帕金森病的神经保护作用。Tovophyllin A 可通过激活 Nrf2 对肝损伤小鼠模型发挥保护作用。Tovophyllin A 对急性肺损伤小鼠有保护性抗炎活性。Tovophyllin A 可抑制 NF-κB 的活化及后续促炎细胞因子的释放。Tovophyllin A 可减少凋亡细胞凋亡 (Apoptosis)。Tovophyllin A 具有抗疟原虫活性。Tovophyllin A 对肺上皮癌细胞和乳腺癌细胞具有细胞毒性活性。Tovophyllin A 可用于帕金森病、肝损伤、急性肺损伤、肺上皮癌以及乳腺癌的相关研究。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
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